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Phytoestrogens: Soy Isoflavones

Isoflavones, Genistein, Daidzein, Glycitein

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Meta Information

ID:phytoestrogens-soy-isoflavones
Name:Phytoestrogens: Soy Isoflavones
Schema Version:1.5

Alternate Names

  • Isoflavones
  • Genistein
  • Daidzein
  • Glycitein

Active Compound

Soy Isoflavones

Intervention Type

therapeutic_agent

Delivery

Route:
oral
Scope:
  • systemic

Regulatory Status

  • us:dietary_supplement

Indication

Focus:
symptom_management
Description:
Alleviating menopausal symptoms and supporting bone health in post-menopausal women.

Typical Protocol

  • For menopausal symptoms, common doses range from 30-100 mg of total isoflavones daily.
  • For bone health support, protocols often suggest 50-100 mg daily over several months.

Expected Cost Mean

Low Cost:
10
High Cost:
40
Cost Type:
monthly
Description:
Monthly cost for supplements, typically not covered by insurance.

Summary

Soy isoflavones are plant-derived compounds with estrogen-like activity that may interact with estrogen receptors. They are primarily studied for their potential role in mitigating menopausal symptoms like hot flashes and supporting bone density. While not a direct anti-aging intervention, they may indirectly contribute to healthspan by addressing specific age-related physiological changes.

Purpose

Mitigates menopausal symptoms, supports bone health; indirect healthspan benefits.

Card Summary

Naturally occurring compounds, soy isoflavones may reduce menopausal symptoms and support bone density, offering indirect healthspan benefits.

Drug Class

null

Drugs In Class

Empty Array

Impact

Score:
4.5
Justification:
Targeted benefits for menopausal symptoms and bone health, indirect healthspan.

Evidence

Grade:
B
Score:
6.5
Justification:
Human trials show moderate efficacy for menopausal symptoms.

Safety

Score:
3
Justification:
Generally safe, but caution with estrogen-sensitive conditions.

Flags

  • May interact with thyroid hormones or antithrombotic medications.
  • Not recommended for individuals with estrogen-sensitive cancers without medical consultation.
  • Potential for mild gastrointestinal upset in some individuals.
  • Long-term effects on specific hormone pathways require more research.

Verdict

May ease menopausal symptoms; consult physician for estrogen-sensitive conditions.