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Myo-inositol

Inositol, Vitamin B8, cis-1,2,3,5-trans-4,6-cyclohexanehexol

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Meta Information

ID:myo-inositol
Name:Myo-inositol
Schema Version:1.5

Alternate Names

  • Inositol
  • Vitamin B8
  • cis-1,2,3,5-trans-4,6-cyclohexanehexol

Active Compound

Myo-inositol

Intervention Type

therapeutic_agent

Delivery

Route:
oral
Scope:
  • systemic

Regulatory Status

  • us:dietary_supplement
  • eu:food_supplement
  • uk:food_supplement

Indication

Focus:
healthspan
Description:
Improves insulin sensitivity, metabolic health, and cellular signaling.

Typical Protocol

  • Take 2 to 4 grams daily, typically divided into two oral doses.
  • Often combined with D-chiro-inositol in a 40:1 ratio to optimize metabolic signaling.

Expected Cost Mean

Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Inexpensive over-the-counter dietary supplement, not covered by health insurance.

Summary

Myo-inositol is a naturally occurring sugar alcohol that acts as an intracellular second messenger in insulin signaling pathways. By facilitating glucose uptake and improving insulin sensitivity, it helps mitigate metabolic dysfunction, a primary driver of biological aging. Its role in cellular signaling also supports neurotransmitter modulation and overall metabolic resilience, making it a valuable targeted tool for extending healthspan.

Purpose

Enhances insulin sensitivity and metabolic signaling for systemic healthspan.

Card Summary

A naturally occurring sugar alcohol that acts as a second messenger to improve insulin sensitivity and metabolic health.

Drug Class

null

Drugs In Class

Empty Array

Impact

Score:
5.5
Justification:
Reliably improves insulin sensitivity and metabolic markers, particularly in insulin-resistant individuals.

Evidence

Grade:
A
Score:
8.5
Justification:
Supported by multiple human RCTs and meta-analyses for metabolic dysfunction.

Safety

Score:
1.5
Justification:
Naturally occurring compound with an excellent safety profile and minimal side effects.

Flags

  • Mild gastrointestinal distress (nausea, gas, diarrhea) may occur at doses exceeding 4 grams daily.
  • May cause additive hypoglycemic effects if combined with insulin-sensitizing drugs like metformin.
  • Bipolar disorder patients should consult a physician, as high doses may trigger manic episodes.

Verdict

Safe, effective targeted supplement for optimizing insulin sensitivity and metabolic health.

Qualifier

scope: systemic, focused on healthspan

Created

2026-05-02T15:08:25.995421Z

Ai Model

Gemini Pro (Low)