Meta Information
ID:l-lysine
Name:L-Lysine
Schema Version:1.5
Title
L-Lysine
Alternate Names
- Lysine
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
5
High Cost:
20
Cost Type:
monthly
Description:
Widely available as a low-cost bulk amino acid supplement.
Summary
L-Lysine is an essential amino acid required for protein synthesis and carnitine production. Its primary clinical use is for suppressing herpes simplex virus (HSV) replication. From a longevity perspective, there is emerging interest in its potential to inhibit the formation of Advanced Glycation End-products (AGEs) by competitively binding to proteins, though robust human evidence for this specific mechanism is currently lacking.
Purpose
Essential amino acid with potential anti-glycation properties.
Card Summary
An essential amino acid studied for viral suppression and potential anti-glycation effects.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
2.8
Justification:
Limited human data for proposed anti-glycation or direct longevity benefits.
Evidence
Grade:
C
Score:
3.5
Justification:
Primarily in-vitro and animal data for anti-glycation; human evidence is lacking.
Safety
Score:
2.5
Justification:
Generally recognized as safe (GRAS) essential amino acid at standard doses.
Flags
- Very high doses (>10-15g/day) may cause gastrointestinal distress.
- Individuals with kidney or liver disease should consult a physician before use.
- May increase calcium absorption; use with caution if taking calcium supplements.
- Potential interaction with aminoglycoside antibiotics, increasing risk of kidney damage.
Verdict
Low-cost but unproven for direct healthspan or longevity benefits.
Created
2026-04-23T23:40:30.928884Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
L-Lysine is an essential amino acid required for protein synthesis and carnitine production. Its primary clinical use is for suppressing herpes simplex virus (HSV) replication. From a longevity perspe...
Typical Protocol
- Daily doses of 1000-3000 mg are common for viral suppression, a proxy for healthspan-related protocols.