Meta Information
ID:l-carnitine
Name:L-Carnitine
Schema Version:1.5
Title
L-Carnitine
Alternate Names
- Acetyl-L-Carnitine
- ALCAR
- Propionyl-L-Carnitine
- L-Carnitine L-Tartrate
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
15
High Cost:
35
Cost Type:
monthly
Description:
Cost for a typical daily dose of a standard L-Carnitine supplement.
Summary
L-Carnitine is an amino acid derivative essential for transporting long-chain fatty acids into the mitochondria to be oxidized for energy. This role is critical for maintaining mitochondrial function, which declines with age. Supplementation may support cellular energy production, reduce oxidative stress, and improve metabolic efficiency, particularly in tissues with high energy demands like muscle and brain.
Purpose
Supports mitochondrial energy production and cellular metabolic efficiency.
Card Summary
An amino acid derivative that transports fatty acids into mitochondria, supporting cellular energy production and potentially mitigating age-related metabolic decline.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Targets mitochondrial energy metabolism, but benefits are most significant in deficient populations.
Evidence
Grade:
B
Score:
6.5
Justification:
Numerous human trials exist, but results for broad healthspan benefits are inconsistent.
Safety
Score:
3.5
Justification:
Generally safe, but high doses can cause GI issues and potential TMAO conversion.
Flags
- May be converted by gut microbiota to TMAO, a metabolite linked to atherosclerosis.
- High doses (>3g/day) can cause nausea, vomiting, and a 'fishy' body odor.
- May increase the effects of anticoagulant drugs like Warfarin.
- Different forms (e.g., ALCAR, LCLT) have distinct bioavailability and targeted effects.
Verdict
A targeted supplement for mitochondrial support, especially if dietary intake is low.
Created
2026-04-23T23:40:17.538118Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
L-Carnitine is an amino acid derivative essential for transporting long-chain fatty acids into the mitochondria to be oxidized for energy. This role is critical for maintaining mitochondrial function,...
Typical Protocol
- Take 500-2000 mg of Acetyl-L-Carnitine (ALCAR) daily, often in divided doses, for cognitive and neurological support.
- Use 1000-2000 mg of L-Carnitine L-Tartrate (LCLT) post-exercise to support muscle recovery and reduce soreness.