Icosapent ethyl, a prescription-grade form of the omega-3 fatty acid EPA, is primarily used in high-risk individuals to lower triglycerides and significantly reduce the risk of major cardiovascular events like heart attacks and strokes. Based on this proven ability to treat a key disease of aging, its role is now expanding into the field of healthspan optimization. By targeting cardiovascular risk through its triglyceride-lowering and anti-inflammatory effects, the intervention aims to extend the period of healthy life by mitigating a primary driver of age-related mortality and disability.
Verdict
A powerful, evidence-backed tool for cardiovascular risk reduction in the right patient.
HEALTHSPAN IMPACT
High Value
RISK LEVEL
Moderate
EVIDENCE GRADE
A
MONTHLY COST
$50 - $350
Protocol
- Take 2 grams twice daily with food for a total of 4 grams per day.
Flags
- Increased risk of atrial fibrillation or atrial flutter requiring hospitalization was observed in clinical trials.
- Associated with an increased risk of bleeding events, use with caution if on other anticoagulant/antiplatelet drugs.
- Requires a prescription and is indicated for specific patient populations with elevated triglycerides and cardiovascular risk.
- Use with caution in patients with a known hypersensitivity to fish or shellfish.