Meta Information
ID:hibiscus-extract
Name:Hibiscus Extract
Schema Version:1.5
Alternate Names
- Roselle extract
- Hibiscus sabdariffa extract
Active Compound
Anthocyanins, phenolic acids, organic acids
Intervention Type
therapeutic_agent
Delivery
Route:
oral
Scope:
- systemic
Regulatory Status
- us:dietary_supplement
- eu:food_supplement
Indication
Focus:
healthspan
Description:
Supports cardiovascular and metabolic health
Typical Protocol
- Typically consumed as 250-1000 mg of standardized extract daily.
- Can be consumed as a tea brewed from dried Hibiscus sabdariffa calyces.
Expected Cost Mean
Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Low-cost dietary supplement or tea, generally not covered by insurance.
Summary
Hibiscus extract, rich in anthocyanins and polyphenols, demonstrates antioxidant and anti-inflammatory properties. It has been shown to support cardiovascular health by helping to lower blood pressure and improve lipid profiles. Its mechanism involves nitric oxide modulation, ACE inhibition, and diuretic effects, contributing to overall vascular and metabolic well-being relevant to healthspan.
Purpose
Supports cardiovascular health, blood pressure, and metabolic balance for healthspan.
Card Summary
Antioxidant-rich extract supporting cardiovascular health, blood pressure, and lipid profiles.
Drug Class
null
Drugs In Class
Empty Array
Impact
Score:
5.5
Justification:
Supports cardiovascular and metabolic health, reducing key risk factors.
Evidence
Grade:
A
Score:
7.8
Justification:
Multiple human RCTs support blood pressure and lipid benefits.
Safety
Score:
2.5
Justification:
Well-tolerated with minimal side effects at typical doses.
Flags
- May lower blood pressure; caution with antihypertensive medications.
- Potential interactions with certain medications, including acetaminophen and hydrochlorothiazide.
- High doses may cause mild stomach upset or temporary dizziness.
Verdict
Supports cardiovascular health; generally safe and well-evidenced.