Meta Information

ID:fluvastatin

Name:Fluvastatin

Schema Version:1.5

Alternate Names

• Lescol
• Lescol XL

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

10

High Cost:

40

Cost Type:

monthly

Description:

Generic prescription cost, often covered by insurance with a co-pay.

Summary

Fluvastatin is a statin medication that lowers LDL cholesterol by inhibiting the HMG-CoA reductase enzyme in the liver. Its primary healthspan relevance is the robust, evidence-based reduction of atherosclerotic cardiovascular disease (ASCVD) risk, a leading cause of age-related mortality and morbidity. While pleiotropic effects like inflammation reduction are studied, its core longevity benefit is preventing heart attacks and strokes.

Purpose

Lowers cholesterol to prevent cardiovascular disease, a major aging driver.

Drug Class

statins

Drugs In Class

Empty Array

Impact

Score:

7.8

Justification:

Massively reduces risk of cardiovascular events, a leading cause of mortality.

Evidence

Grade:

A

Score:

9.5

Justification:

Extensive, large-scale human RCTs and meta-analyses confirm cardiovascular risk reduction.

Safety

Score:

4.8

Justification:

Well-tolerated but carries risks of myopathy and new-onset diabetes.

Flags

• Requires a prescription and medical supervision.
• Common side effects include muscle pain (myalgia) and elevated liver enzymes.
• Associated with a small but statistically significant increased risk of developing type 2 diabetes.
• Rare but serious risk of rhabdomyolysis (severe muscle breakdown).
• Interacts with grapefruit juice and certain antifungal or antibiotic medications.

Verdict

A cornerstone for cardiovascular risk reduction, but requires medical supervision.

Created

2026-04-27T00:50:58.251635Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

disease_treatment

Description:

Fluvastatin is a statin medication that lowers LDL cholesterol by inhibiting the HMG-CoA reductase enzyme in the liver. Its primary healthspan relevance is the robust, evidence-based reduction of athe...

Typical Protocol

• Daily oral dose of 20-80mg, prescribed based on cardiovascular risk assessment.