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Epitalon

Epithalon, Epithalamin, Ala-Glu-Asp-Gly

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Meta Information

ID:epitalon
Name:Epitalon
Schema Version:1.5

Title

Epitalon

Alternate Names

  • Epithalon
  • Epithalamin
  • Ala-Glu-Asp-Gly

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
75
High Cost:
200
Cost Type:
one time
Description:
Cost per 10-20 day cycle, typically repeated semi-annually.

Summary

Epitalon is a synthetic tetrapeptide designed to mimic epithalamin, a peptide naturally produced by the pineal gland. Its primary proposed mechanism for healthspan is the upregulation of the telomerase enzyme, which helps maintain or lengthen telomeres, the protective caps on the ends of chromosomes. By counteracting telomere shortening, a hallmark of cellular aging, Epitalon is theorized to slow age-related decline and extend cellular lifespan.

Purpose

Synthetic peptide theorized to lengthen telomeres and regulate circadian rhythm.

Card Summary

A synthetic peptide studied for its potential to lengthen telomeres by activating the telomerase enzyme, theoretically slowing a key mechanism of cellular aging.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
3.2
Justification:
Theorized to impact a fundamental aging process but lacks robust human data.

Evidence

Grade:
C
Score:
3.5
Justification:
Primarily based on older Russian animal and small human cohort studies.

Safety

Score:
7.8
Justification:
Unregulated research chemical with no long-term human safety data from major trials.

Flags

  • Not approved for human use by the FDA or EMA.
  • Sourced from unregulated 'research chemical' suppliers, risking purity and contamination issues.
  • Most supporting research originates from a single institution with limited independent validation.
  • Long-term effects of telomerase activation, including theoretical cancer risk, are unknown.

Verdict

A highly speculative peptide with significant safety and evidence concerns.

Created

2026-04-23T23:27:32.575504Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
subcutaneous_injection
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
Epitalon is a synthetic tetrapeptide designed to mimic epithalamin, a peptide naturally produced by the pineal gland. Its primary proposed mechanism for healthspan is the upregulation of the telomeras...

Typical Protocol

  • A common cycle is 10 mg daily via subcutaneous injection for 10-20 days, repeated every 6 months.