Elderberry (Sambucus nigra) fruit extract contains anthocyanins and other flavonoids known for their antioxidant and anti-inflammatory properties. While widely used for immune support during seasonal illness, its direct role in extending healthspan or significantly impacting aging pathways is not established by robust human evidence. It primarily functions to modulate immune responses to viral infections.
Verdict
Useful for acute immune support, but not a healthspan intervention.
HEALTHSPAN IMPACT
Experimental
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$10 - $30
Protocol
- Standard dosages range from 150-300 mg of elderberry extract, standardized to anthocyanins, taken 2-4 times daily for a few days at the onset of cold or flu symptoms.
Flags
- Raw or unripe elderberries contain cyanogenic glycosides and are toxic, causing nausea, vomiting, and diarrhea.
- Potential for interaction with immunosuppressant drugs due to immune-stimulating effects.
- Individuals with autoimmune diseases should use with caution.