Meta Information

ID:dihexa

Name:Dihexa

Schema Version:1.5

Alternate Names

• N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
• PNA-11

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

30

High Cost:

80

Cost Type:

monthly

Description:

Cost for research-grade peptide from online suppliers; not covered by insurance.

Summary

Dihexa is a synthetic peptide designed to be a potent activator of Hepatocyte Growth Factor (HGF) and its receptor, c-Met. In animal models, this activation promotes the formation of new synapses (synaptogenesis) and has shown potential in repairing neurological damage. Its relevance to healthspan is purely theoretical, focusing on the potential to counteract age-related cognitive decline and neurodegeneration, but it completely lacks human clinical data.

Purpose

An experimental peptide studied for neurogenesis and cognitive repair.

Card Summary

An experimental peptide that may enhance cognitive function by promoting new neural connections, but lacks human evidence.

Drug Class

Drugs In Class

Empty Array

Impact

Score:

2.1

Justification:

Theoretically potent neurogenic effects but lacks any human clinical trial data.

Evidence

Grade:

C

Score:

3

Justification:

Evidence is limited to preclinical animal models and in-vitro studies.

Safety

Score:

8.8

Justification:

Research chemical with no human safety trials, sourced from unregulated suppliers.

Flags

• Completely lacks human safety, dosing, or efficacy data.
• Sourced from unregulated 'research chemical' suppliers, posing a high risk of contamination or incorrect dosage.
• Long-term effects of potent HGF/c-Met activation are unknown and pose a theoretical cancer risk.
• Not approved for human consumption by any regulatory agency.

Verdict

A highly speculative research chemical with no human data; avoid.

Model

Gemini 3.1 Pro (High)

Delivery

Route:

subcutaneous_injection

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Dihexa is a synthetic peptide designed to be a potent activator of Hepatocyte Growth Factor (HGF) and its receptor, c-Met. In animal models, this activation promotes the formation of new synapses (syn...

Typical Protocol

• As a research chemical, no established human protocol exists; anecdotal use involves topical or injected low-milligram doses.