This combination therapy pairs Vitamin D3, a prohormone crucial for calcium absorption and immune regulation, with Vitamin K2, which directs that calcium to bones and away from arteries. The liposomal delivery system aims to enhance the bioavailability of these fat-soluble vitamins, potentially improving their efficacy in supporting skeletal and cardiovascular health, key pillars of healthspan.
Verdict
A foundational supplement for bone, immune, and cardiovascular healthspan.
HEALTHSPAN IMPACT
High Value
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$20 - $50
Protocol
- Daily doses typically range from 1,000-5,000 IU of Vitamin D3.
- Vitamin K2 (as MK-7) is commonly dosed from 90-200 mcg per day.
- Best taken with a meal containing fat to enhance absorption of these fat-soluble vitamins.
- Regular blood testing (25-hydroxyvitamin D) is recommended to guide dosing and avoid toxicity.
Flags
- Excessive Vitamin D can lead to hypercalcemia (high blood calcium), a serious condition.
- Vitamin K can interfere with anticoagulant drugs like Warfarin (Coumadin); consult a physician.
- Regular blood testing of 25(OH)D levels is crucial to personalize dosage and prevent toxicity.