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Copper Peptides (Topical)

GHK-Cu, Glycyl-L-Histidyl-L-Lysine

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Meta Information

ID:copper-peptides
Name:Copper Peptides
Schema Version:1.5

Alternate Names

  • GHK-Cu
  • Glycyl-L-Histidyl-L-Lysine

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
20
High Cost:
150
Cost Type:
monthly
Description:
Cost for a 30-day supply of a quality topical serum or cream.

Summary

Copper peptides, particularly GHK-Cu, are naturally occurring protein fragments with a high affinity for copper ions. They are believed to support healthspan primarily by promoting skin rejuvenation, stimulating collagen and elastin production, accelerating wound healing, and exerting anti-inflammatory and antioxidant effects. While most evidence supports topical benefits for skin health, research explores their potential for systemic tissue repair.

Purpose

Supports skin rejuvenation, wound healing, and reduces local inflammation.

Card Summary

A topical agent that promotes skin repair, collagen synthesis, and reduces inflammation.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
4.2
Justification:
Primarily benefits skin aesthetics and health with limited evidence for systemic longevity effects.

Evidence

Grade:
B
Score:
6.5
Justification:
Human trials exist for cosmetic endpoints, but systemic healthspan data is lacking.

Safety

Score:
2.5
Justification:
Topical use is well-tolerated with a low risk of skin irritation.

Flags

  • Systemic (injectable) use lacks long-term human safety data and is highly experimental.
  • Product quality and peptide concentration can vary significantly between brands.
  • Potential for skin irritation or allergic reaction in sensitive individuals.
  • Excess systemic copper can be pro-oxidant; oral/injectable use requires careful consideration.

Verdict

A promising topical agent for skin health, not a systemic longevity intervention.

Created

2026-04-26T21:56:48.006352Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
topical_skin
Scope:
  • local

Is Skin Health

True

Indication

Focus:
healthspan
Description:
Copper peptides, particularly GHK-Cu, are naturally occurring protein fragments with a high affinity for copper ions. They are believed to support healthspan primarily by promoting skin rejuvenation, ...

Typical Protocol

  • Apply a 1-3% concentration serum or cream to the face or scalp once daily.
  • Injectable forms are used experimentally and lack standardized healthspan protocols.