Meta Information
ID:cjc-1295
Name:CJC-1295
Schema Version:1.5
Title
CJC-1295
Alternate Names
- CJC-1295 with DAC
- Modified GRF (1-29) with DAC
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
160
High Cost:
320
Cost Type:
monthly
Description:
Sourced from compounding pharmacies or research chemical suppliers.
Summary
CJC-1295 is a long-acting synthetic analogue of Growth Hormone Releasing Hormone (GHRH). It stimulates the pituitary gland to release growth hormone (GH) in a more natural, pulsatile manner, which in turn increases levels of Insulin-like Growth Factor 1 (IGF-1). For healthspan, the goal is to restore youthful GH/IGF-1 levels to support tissue repair, body composition, and sleep quality, though the long-term effects on aging are still debated.
Purpose
A long-acting GHRH analogue to increase endogenous growth hormone.
Card Summary
A long-acting peptide that stimulates natural growth hormone release for tissue repair.
Drug Class
ghrh-analogue
Drugs In Class
Empty Array
Impact
Score:
5.5
Justification:
Effectively raises GH/IGF-1 for body composition, but long-term healthspan impact is unproven.
Evidence
Grade:
B
Score:
5
Justification:
Small human trials exist but lack long-term healthspan or mortality data.
Safety
Score:
7.5
Justification:
Injectable research chemical with unknown long-term risks and potential for serious side effects.
Flags
- Requires subcutaneous injection and sterile technique.
- Long-term elevation of IGF-1 is controversially linked to increased cancer risk.
- Often sourced from unregulated 'research chemical' suppliers, posing quality and purity risks.
- Should not be used by individuals with active or suspected cancer.
- Potential side effects include water retention, joint pain, and nerve compression.
- Interacts with corticosteroids, which can blunt the GH-releasing effect.
Verdict
Potent GH booster with unproven longevity benefits and significant safety concerns.
Created
2026-04-23T23:09:53.421844Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
subcutaneous_injection
Scope:
- systemic
Indication
Focus:
healthspan
Description:
CJC-1295 is a long-acting synthetic analogue of Growth Hormone Releasing Hormone (GHRH). It stimulates the pituitary gland to release growth hormone (GH) in a more natural, pulsatile manner, which in ...
Typical Protocol
- 1000-2000 mcg administered subcutaneously once or twice per week due to its long half-life.