Meta Information
ID:cinnamon-extract
Name:Cinnamon Extract
Schema Version:1.5
Alternate Names
- Cinnamomum verum
- Cinnamomum cassia
- Ceylon Cinnamon
- Cassia Cinnamon
Active Compound
Cinnamaldehyde
Intervention Type
therapeutic_agent
Delivery
Route:
oral
Scope:
- systemic
Regulatory Status
- us:dietary_supplement
- eu:food_supplement
Indication
Focus:
healthspan
Description:
Primarily used for supporting healthy blood glucose levels, improving insulin sensitivity, and providing antioxidant effects.
Typical Protocol
- Standardized extracts are often taken at 250-500 mg, one to two times per day with meals.
- For whole powder, doses typically range from 1 to 6 grams daily, split between meals.
- Ceylon ('true') cinnamon is preferred over Cassia cinnamon for long-term supplementation due to lower coumarin content.
Expected Cost Mean
Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Widely available over-the-counter supplement; not covered by insurance.
Summary
Cinnamon extract contains bioactive compounds like cinnamaldehyde and polyphenols that appear to improve insulin sensitivity and glucose metabolism. By mimicking insulin and enhancing cellular glucose uptake, it may help manage blood sugar levels. Its antioxidant and anti-inflammatory properties could also contribute to mitigating age-related metabolic dysfunction, a key aspect of healthspan.
Purpose
Supports metabolic health by improving insulin sensitivity and glucose control.
Card Summary
A common spice extract that may improve insulin sensitivity and support healthy blood glucose levels, potentially mitigating age-related metabolic decline.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Provides moderate, targeted benefits for glucose metabolism and insulin sensitivity.
Evidence
Grade:
A
Score:
8.5
Justification:
Supported by multiple human RCTs and meta-analyses for improving glycemic control.
Safety
Score:
3.5
Justification:
Generally safe, but Cassia varieties contain coumarin, posing a liver risk at high doses.
Flags
- Cassia cinnamon contains high levels of coumarin, which can be toxic to the liver in large, chronic doses; Ceylon cinnamon is preferred.
- May lower blood sugar; use with caution alongside diabetes medications to avoid hypoglycemia.
- The coumarin in Cassia cinnamon may interact with blood-thinning medications like warfarin.
Verdict
A well-evidenced supplement for supporting healthy blood glucose levels.
Created
2026-05-15T15:18:54.275983Z
Ai Model
Gemini 2.5 Pro (High)