Chondroitin Sulfate

Chondroitin sulfate is a major structural component of cartilage, helping it retain water and resist compression. For healthspan, its primary role is preserving joint function and mobility, which are critical for maintaining an active lifestyle into old age. By potentially reducing cartilage breakdown and associated low-grade inflammation, it may help mitigate a key aspect of 'inflammaging'.

Verdict

A safe, well-studied supplement for targeted joint health and mobility support.

Protocol

• Daily dosages of 800-1200 mg, often taken in divided doses, are used for joint health.

Flags

• May have mild blood-thinning effects; use with caution if taking anticoagulants like warfarin.
• Often derived from animal sources (e.g., bovine, shark), a consideration for vegans or those with allergies.
• Supplement quality and bioavailability can vary significantly between manufacturers.