Meta Information

ID:chamomile-extract

Name:Chamomile Extract

Schema Version:1.5

Alternate Names

• Matricaria recutita
• Chamaemelum nobile
• Apigenin

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

10

High Cost:

30

Cost Type:

monthly

Description:

Widely available over-the-counter supplement; not covered by insurance.

Summary

Chamomile extract contains bioactive compounds, notably the flavonoid apigenin, which exerts mild sedative and anxiolytic effects by binding to benzodiazepine receptors in the brain. Its primary relevance to healthspan is through the improvement of sleep quality, a critical process for cellular repair, hormonal regulation, and cognitive function. Secondary benefits may arise from its modest anti-inflammatory and antioxidant properties.

Purpose

A plant extract used to improve sleep quality and reduce anxiety.

Card Summary

A mild sedative and anti-inflammatory plant extract primarily used to improve sleep quality.

Drug Class

Drugs In Class

Empty Array

Impact

Score:

4.2

Justification:

Primarily supports sleep quality, a key healthspan pillar, with mild anxiolytic effects.

Evidence

Grade:

B

Score:

6.5

Justification:

Human RCTs show modest benefits for sleep quality and generalized anxiety disorder.

Safety

Score:

2.5

Justification:

Generally recognized as safe (GRAS) with rare allergic reactions being the primary concern.

Flags

• Potential for allergic reaction in individuals sensitive to the Asteraceae family (e.g., ragweed).
• May interact with sedatives, blood thinners (e.g., warfarin), and anti-platelet drugs.
• May affect the metabolism of drugs processed by cytochrome P450 enzymes.

Verdict

A safe, mild intervention for improving sleep quality and reducing anxiety.

Created

2026-04-26T17:45:01.734966Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Chamomile extract contains bioactive compounds, notably the flavonoid apigenin, which exerts mild sedative and anxiolytic effects by binding to benzodiazepine receptors in the brain. Its primary relev...

Typical Protocol

• Take 250-500 mg of standardized extract (1.2% apigenin) 30-60 minutes before bedtime.