Meta Information
ID:carnosine-eye-drops
Name:Carnosine Eye Drops
Schema Version:1.5
Alternate Names
- N-acetylcarnosine eye drops
- NAC eye drops
- Can-C
Active Compound
L-carnosine
Intervention Type
therapeutic_agent
Delivery
Route:
eye
Scope:
- local
Regulatory Status
- us:otc_drug
- us:cosmetic
Indication
Focus:
healthspan
Description:
Aimed at mitigating age-related decline in eye health, particularly lens clouding (cataracts) and general oxidative stress.
Typical Protocol
- Apply 1-2 drops of a 1% N-acetylcarnosine solution to each eye, two times per day.
Expected Cost Mean
Low Cost:
20
High Cost:
40
Cost Type:
monthly
Description:
Cost for one or two bottles for a month's supply; not insurance covered.
Summary
Carnosine is an antioxidant and anti-glycating dipeptide naturally present in tissues. In the eye, it is proposed to protect the lens proteins from cross-linking and oxidation, which are key drivers of age-related cataract formation. N-acetylcarnosine (NAC) is a more stable form used in eye drops that is converted to carnosine within the eye, potentially slowing the progression of lens opacification.
Purpose
Antioxidant eye drops to combat age-related lens clouding and oxidative stress.
Card Summary
Topical antioxidant eye drops intended to slow the progression of age-related cataracts by reducing glycation and oxidative damage in the lens.
Drug Class
null
Drugs In Class
Empty Array
Impact
Score:
3.5
Justification:
Limited human data suggests potential for slowing cataract progression, but lacks robust validation.
Evidence
Grade:
B
Score:
4.5
Justification:
Based on small human trials, primarily from one research group, lacking large-scale replication.
Safety
Score:
2.5
Justification:
Topical application with minimal systemic absorption; main side effect is temporary eye irritation.
Flags
- Primary side effect is temporary stinging or burning upon application.
- Efficacy for reversing existing cataracts is not supported by strong evidence.
- Should not be used as a substitute for professional ophthalmological care or surgery.
- Ensure the product is sterile and from a reputable manufacturer.
Verdict
A low-risk, experimental approach for potentially slowing early-stage cataract progression.
Qualifier
route: eye, scope: local, focused on healthspan
Created
2026-05-07T02:00:22.354457Z
Ai Model
Gemini 2.5 Pro (High)