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Blueprint Protocol

Bryan Johnson's Blueprint

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Meta Information

ID:blueprint-protocol
Name:Blueprint Protocol
Schema Version:1.5

Title

Blueprint Protocol

Alternate Names

  • Bryan Johnson's Blueprint

Intervention Type

dietary_practice

Expected Cost Mean

Low Cost:
2000
High Cost:
10000
Cost Type:
monthly
Description:
Covers extensive supplements, organic foods, and frequent diagnostic testing; medical staff is extra.

Summary

Blueprint is a comprehensive, data-driven protocol designed to systematically measure and attempt to reverse biological age across all major organ systems. It combines a specific diet, a large regimen of targeted supplementation, specific exercise routines, and sleep optimization, all guided by continuous biomarker tracking to inform adjustments.

Purpose

A comprehensive, data-driven system to slow and reverse biological aging.

Card Summary

A highly rigorous, data-driven protocol combining diet, exercise, and supplementation to systematically reverse biological age, guided by extensive biomarker tracking.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
8.5
Justification:
Aims to be a foundational, systemic intervention by targeting all major organ systems.

Evidence

Grade:
D
Score:
1
Justification:
An n-of-1 experiment; lacks formal clinical trials or peer-reviewed data on the protocol.

Safety

Score:
7
Justification:
Extreme supplementation and off-label drug use require intensive medical supervision to manage risks.

Flags

  • The protocol's efficacy and safety as a whole have not been validated in clinical trials.
  • Extremely high cost and time commitment make it inaccessible for most people.
  • Potential for unknown interactions between the large number of supplements and medications.
  • Requires a dedicated medical team for monitoring and adjustments.

Verdict

A pioneering but unproven n-of-1 experiment in radical healthspan optimization.

Created

2026-04-23T22:56:55.877786Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
none
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
Blueprint is a comprehensive, data-driven protocol designed to systematically measure and attempt to reverse biological age across all major organ systems. It combines a specific diet, a large regimen...

Typical Protocol

  • Involves a strict vegan diet, extensive daily supplementation, specific exercise routines, and regular medical testing.
  • Adherence to a precise daily schedule for sleep, meals, and activities is central to the protocol.