Meta Information
ID:bakuchiol-serum
Name:Bakuchiol Serum
Schema Version:1.5
Alternate Names
- Bakuchiol
Active Compound
bakuchiol
Intervention Type
therapeutic_agent
Delivery
Route:
topical_skin
Scope:
- local
Is Skin Health
True
Regulatory Status
- us:cosmetic
Indication
Focus:
symptom_management
Description:
Reduces the appearance of fine lines, wrinkles, and improves skin texture and tone.
Typical Protocol
- Apply a few drops of serum to clean, dry skin once or twice daily, typically at night.
Expected Cost Mean
Low Cost:
20
High Cost:
60
Cost Type:
monthly
Description:
Cost of a single bottle of bakuchiol serum, not typically covered by insurance.
Summary
Bakuchiol is a plant-derived meroterpene that mimics retinol's effects on gene expression related to collagen production and cellular turnover, but with less irritation. It supports skin health by reducing the appearance of photoaging, fine lines, and wrinkles. While beneficial for skin aesthetics, its direct impact on systemic healthspan beyond the integumentary system is not established.
Purpose
Improves skin texture, reduces wrinkles, supports epidermal integrity, and manages visible aging.
Card Summary
Plant-derived compound mimicking retinol's anti-aging effects on skin without irritation.
Drug Class
null
Drugs In Class
Empty Array
Impact
Score:
5
Justification:
Effective for improving skin aesthetics; limited systemic healthspan impact.
Evidence
Grade:
B
Score:
7
Justification:
Multiple human trials demonstrate efficacy for skin aging and texture.
Safety
Score:
3
Justification:
Generally well-tolerated, mild irritation possible, less than retinol.
Flags
- Mild skin irritation or sensitivity may occur, especially during initial use.
- Patch testing recommended before full application to assess individual sensitivity.
Verdict
Promising plant-derived retinol alternative for improved skin appearance.